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In certain experiments, it has been observed that RNA is often considered to be more fragile than DNA.The chemical instability of RNA and the ubiquitous presence of RNase make RNA extremely susceptible to degradation. Degraded RNA often leads to unsatisfactory results in downstream experiments. T...Read more »

In 1983, American biochemist Kary Mullis conceived the idea of in vitro amplification of nucleic acids, and in 1985, he invented the process known as polymerase chain reaction (PCR), giving birth to the PCR technique. In 1988, Saiki et al. successfully completed the automatic amplification of DNA...Read more »

Are you having trouble with high Ct values and poor repeatability? Find out whether issues are caused by low gene expression, and check out tips on how to optimize your experiment to resolve these issues!   What is a low-expression gene? Low-expression gene usually refer to those genes with low r...Read more »

  Adapters are an essential part of library preparation. Similar to NGS technologies, they are constantly evolving. Feeling overwhelmed with the mind-boggling variety of adapters available on the market? Worry not! Let’s walk through everything you need to know about adapters.   Adapters are nucl...Read more »

DNA plays a crucial role in human growth and development. Irreparable DNA damage caused by external environmental factors leads to disease, which may be transmitted to future generations through genetic material. Common genetic disorders in humans can be divided into four broad categories: chromo...Read more »

Vazyme (688105.SH), China's leading biotechnology company, has officially signed a global strategic cooperation agreement with Azenta Life Sciences (“Azenta”, Nasdaq: AZTA), which will promote to establish “one-stop” service process for both companies in the fields of ne...Read more »

Next-Generation Sequencing (NGS) is a disruptive technology that is reshaping our understanding of biological science and revolutionizing human health. With its broad applications in genomics, disease diagnosis, and reproduction, NGS shows immense potential. Recognizing ...Read more »

In an era of technological advancements, the quest for human health knows no bounds. Next-Generation Sequencing (NGS) stands as a revolutionary biotechnology that unravels the mysteries of human life. Since 2014, Vazyme has noticed this promising technology and started i...Read more »

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On November 14, Vazyme held an online celebration for the 10th anniversary of its founding and the 1st anniversary of its IPO. In his speech, Chairman Cao Lin expressed his gratitude to customers, partners and investors for their constant trust and support, and paid trib...Read more »

Vazyme Releases 2022 Semi-Annual Report: On Track to Be a Biotech Leader    Revenue hit $242 million, up 96.2% y-o-y.Net profit reached $92 million, up 56.67% y-o-y.R&D investment stood at $23 million, up 85.72% y-o-y. Vazyme recently released the 2022 semi-annual re...Read more »

Title: WUSCHEL triggers innate antiviral immunity in plant stem cells Journal: Science Impact Factor: 63.71 Vazyme Product: HiScript III RT SuperMix for qPCR (+gDNA wiper) [Vazyme #R323, for Two-step RT-qPCR] Research Background The cultivation of virus-free plants is o...Read more »

Background Cholera, is an acute diarrheal disease caused by infection of the small intestine through certain pathogenic strains of Vibrio cholerae1. Cholera usually develops immediately after exposure to the pathogen, and symptoms can be either mild or quite severe2. The...Read more »

Introduction Cirrhosis and other chronic liver diseases (collectively referred to herein as cirrhosis) are one of the major causes of morbidity and mortality worldwide1. Spontaneous bacterial peritonitis (SBP) is a common and potentially fatal complication of liver cirrh...Read more »

Background At the beginning of 2020, in the face of the sudden outbreak of COVID-19, nucleic acid testing became widely known. As one of the main detection methods in the field of IVD, nucleic acid detection kits have developed rapidly in recent years, especially in the ...Read more »

Request Your Quote Today! Vazyme Molecular diagnosis is a versatile and precise tool that employs nucleic acid-based techniques. It can be used to detect infectious diseases (e.g., respiratory diseases and...Read more »

Foreword Do you feel that it is too cumbersome to do two steps of reverse transcription? Are you concerned that double pipetting increases the risk of RNA degradation? Then you must try this HiScript® III All-in-one...Read more »

International Infection Status According to the World Health Organization (WHO), from May 13, 2022 to June 8, 2022, Monkeypox has spread to the Americas, Eastern Mediterranean, Europe, and Western Pacific regions. Twenty-eight countries in the four regions have reported ...Read more »

In scientific research, we often hear about SNP, but what exactly is SNP, why do we study SNP, and how do we carry out research work? Let's take a look below. What exactly is SNP Single nucleotide polymorphism (SNP) refers to the diversity of DNA sequences caused by sing...Read more »

Title: Phytocytokine signalling reopens stomata in plant immunity and water loss Journal: Nature IF: 49.962 Author and Unit: Texas A&M University-Libo Shan, Ping He and Shandong Jianzhu University-Shuguo Hou are the co-corresponding authors of this article. Vazyme Co...Read more »

The COVID-19 epidemic has not yet subsided, and mysterious hepatitis has broken out all over the world, quickly reaching out "poisonous hands" to children. On 5 April 2022, the International Health Regulations (IHR) National Focal Point (NFP) for the United Kingdom first...Read more »

1.Monkeypox virus infection status According to the news of the United Nations on May 22, the World Health Organization (WHO) has reported 92 confirmed cases and 28 suspected cases in 12 non monkeypox virus endemic countries around the world since May 13 (Table 1 for det...Read more »

Product Description 5 min TOPO-Blunt Cloning Kit is the third generation TOPO cloning kit, which contains Topoisomerase, vector and self-ligation inhibitory factor. The kit utilizes a new type of Topoisomerase, with the optimal buffer, the enzyme activity is higher, and ...Read more »

Basic Information Title: ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma Journal: Molecular Cancer  Impact factor: 27.401 Vazyme product:  HiScript III 1st Strand cDNA Synthesis Kit (+gDNA wiper) (Vazyme #R312, for cDNA one-str...Read more »

With the continuous increase in the quantity of COVID-19 test in recent days, the test report that can be obtained in the usual 6 – 8 hours may be delayed, which is not conducive to quickly blocking the social spread of the COVID-19. The use of supporting instrument (capable of rapid test) ...Read more »

Since the invention of polymerase chain reaction (PCR) by Kary Mullis in 1983, the technology has played an important role in the field of life sciences, for which Mullis won the Nobel Prize in Chemistry in 19931. In 1988, Saiki et al. successfully completed the automatic amplification of DNA wit...Read more »

Background Taq polymerase is the tried and true standard when it comes to PCR, but that doesn’t mean it’s the most accurate polymerase for high-sensitivity applications. Conversely, alternative enzymes, called high-fidelity polymerases, provide greater accuracy in PCR-generated amplic...Read more »

Background Over the past two decades, the world has faced several infectious disease outbreaks. Ebola, Influenza A (H1N1), SARS, MERS and Zika virus have had a massive global impact in terms of economic disruption, strain on local and global public health resources and, above all, human health (B...Read more »

Basic Information Title: The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity Journal: Nature   Impact factor: 49.962 Vazyme product: ChamQ Universal SYBR qPCR Master Mix (Vazyme #Q711, for SYBR Green qPCR detection)  Research Background Introduction N6-methyladenosine...Read more »

The novel coronavirus (SARS-CoV-2) pandemic has led to a public health crisis1. Delta and Lambda SARS-CoV-2 variants have appeared in more than 90 countries around the world2. How to quickly and accurately diagnose the virus, especially the variant strain, is of great significance to the treatmen...Read more »

The SARS-CoV-2 Omicron variant has rapidly displaced the Delta variant as the major prevalent variant in most of the world. The Omicron variant harbors more than 60 mutations, and 15 of the mutations are located in the receptor-binding domain (RBD)1. The L452R mutation is one of the most common m...Read more »